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Von Brunn’s Nests
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- Normal urothelium is 5-7 cells thick with umbrella, intermediate, and basal cells (see normal histology section)
- Von Brunn’s nests are considered a "normal" finding on biopsies, and may be identified in 85-95% of patients, particularly in the region of the trigone.
- Histologic features:
- well-circumscribed nests of benign urothelial cells within the lamina propria
- may or may not have an obvious connection to the overlying mucosal surface
- most commonly identified in the trigone of the bladder
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