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Infarcts with Squamous Metaplasia
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- 20-25% of BPH specimens have infarcts
- Patients may present with acute retention due to a sudden increase in the size of the prostate
- Gross: mottled and yellowish, or may appear hemorrhagic
- Histologic features: typically shows three zones
- central zone of coagulative necrosis (everything looks reddish with faint outlines of the cells, like “ghost cells”)
- middle zone of hemorrhage and inflammation
- peripheral zone of glands with squamous metaplasia
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