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Pathology | Testis I - [click on image(s) below]

Anorchidism

  1. Both monorchidism and testicular regression syndrome display similar histologic features:
    • absence of testicular parenchyma
    • presence of vas deferens, epididymis, or small groups of seminiferous tubules (69-83% of cases)
    • spermatic vessels are small in 83% of cases
    • areas of dystrophic calcifications, hemosiderin deposition, or giant cell reaction may be found within the mass that is noted instead of a testis
  2. Etiology: two hypotheses have been proposed: either it represents a primary anomaly of the gonad or it represents atrophy of the testis secondary to a vascular lesion, such as thrombosis or intrauterine torsion -- a theory that may be supported by the common finding of hemosiderin in the area adjacent to the regressed testis...
  3. Associations:
    • absence of the kidney
    • cystic seminal vesicles
    • ipsilateral renal dysgenesis