American Urological Association - Adenocarcinoma of Rete Testis
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Adenocarcinoma of Rete Testis

  • Exceedingly rare.
  • Occurs in a wide age range, although mostly in older adults (>60 years old).
  • May present as a large painful scrotal mass.
  • Gross: white gray infiltrative mass centered at the testicular hilum.
  • Histology:
    • Solid, papillary, or tubulopapillary growths in a desmoplastic stroma.
    • Nuclear stratification, moderate to marked pleomorphism, and with frequent mitosis.
    • Key to diagnosis is to see transitions from normal rete testis epithelium to adenocarcinoma.
  • Poor prognosis with advanced disease.