American Urological Association - Fournier's Gangrene
- Necrotizing fasciitis of the subcutaneous tissue and skeletal muscle of the genitals and perineum, especially the scrotum (image A).
- Causative agents: staphylococcal or streptococcal species.
- Clinical: lesions begin as reddish plaques with necrosis; often associated with systemic symptoms, including pain and fever.
- Predisposing factors: diabetes mellitus, immunosuppression, alcoholism, recent surgical intervention, trauma, and morbid obesity.
- Histologic features: nonspecific: essentially acute inflammatory infiltrate with necrotic tissue and bacteria (image B), (image C), & (image D).
- Treatment: surgical intervention, antibiotics; may be life-threatening.