American Urological Association - Reactive Transitional Cells
Reactive Transitional Cells
- Once again, the first thing to do is establish how the specimen is received. One clue (image A) is the dense purple "blob" at the right side of the picture: this represents K-Y jelly; therefore, we can assume these are washings/brushings.
- Cytologic features to look for:
- Cells maintain smooth, round nuclear borders with evenly distributed chromatin (image B).
- Nuclei may be slightly enlarged with small punctate cherry-red nucleoli.
- Binucleation and multinucleation is common, especially in the umbrella cells.
- Clusters and sheets do not have fibrovascular cores.
- Cells still "respect" each other's borders.
- Background is relatively clean, without necrosis or debris.