EDUCATION > Educational Programs > E-Learning > Pathology for Urologists

Pathology for Urologists

Cystitis Glandularis

Image A
(click on the image above)

Image B
(click on the image above)

  • Reactive glandular metaplasia of epithelium found in 71% of bladders, most often as an incidental finding.
  • When visualized, by cystoscopy appears as red raised nodular lesions, with predilection for trigone.
    • Rarely, extensive intestinal metaplasia may have copious mucin extravasation that may form pseudotumorous mass lesion.
  • Histology: 2 histologic types.
    • Typical type: similar to cystitis cystica but with luminal cuboidal or columnar cells surrounded by urothelial cells (image A) & (image B).

Image C
(click on the image above)

Image D
(click on the image above)

  • Intestinal type: identical to typical cystitis glandularis but with presence of goblet cells
    (image C) & (image D).
  • In patients with long-standing inflammation (indwelling catheters, calculi, etc.), intestinal type cystitis glandularis may become diffuse, at which time is suggested as a possible risk for bladder adenocarcinoma, although this association is currently controversial.

    Term of Use

    © 2017 American Urological Association Education and Research Inc. All Rights Reserved.