EDUCATION > Educational Programs > E-Learning > Pathology for Urologists

Pathology for Urologists

Reactive Transitional Cells

Image A
(click on the image above)

Image B
(click on the image above)

  • Once again, the first thing to do is establish how the specimen is received. One clue (image A) is the dense purple "blob" at the right side of the picture: this represents K-Y jelly; therefore, we can assume these are washings/brushings.
  • Cytologic features to look for:
    • Cells maintain smooth, round nuclear borders with evenly distributed chromatin (image B).
    • Nuclei may be slightly enlarged with small punctate cherry-red nucleoli.
    • Binucleation and multinucleation is common, especially in the umbrella cells.
    • Clusters and sheets do not have fibrovascular cores.
    • Cells still "respect" each other's borders.
    • Background is relatively clean, without necrosis or debris.


Term of Use

© 2017 American Urological Association Education and Research Inc. All Rights Reserved.