Pathology for Urologists
Adenocarcinoma of Rete Testis
- Exceedingly rare.
- Occurs in a wide age range, although mostly in older adults (>60 years old).
- May present as a large painful scrotal mass.
- Gross: white gray infiltrative mass centered at the testicular hilum.
- Solid, papillary, or tubulopapillary growths in a desmoplastic stroma.
- Nuclear stratification, moderate to marked pleomorphism, and with frequent mitosis.
- Key to diagnosis is to see transitions from normal rete testis epithelium to adenocarcinoma.
- Poor prognosis with advanced disease.