Pathology for Urologists
Plasma Cell Balanitis (Zoon's Balanitis)
- General: The term balanitis refers to inflammation of the glans penis, while balanoposthitis refers to inflammation of the glans and prepuce; both entities are most often seen in uncircumcised males due to poor hygiene and accumulation of smegma beneath the foreskin, but other causes include candida, BXO, contact dermatitis, etc.
- Plasma cell balanitis (Zoon's balanitis).
- Also known as balanitis circumscripta plasmacellularis (in females: vulvitis circumscripta plasmacellularis).
- Affects only uncircumcised males, and is thought to represent a reaction to a multitude of diverse stimuli.
- Gross: single large (>2 cm) bright red moist patch on the glans or inner prepuce.
- Distinct upper dermal band-like infiltrate containing plasma cells.
- Dermis contains dilated capillaries and the epidermis may be thin or partially absent.
- Intracellular edema may be prominent.