Clinical: single or multiple small papules that coalesce to form ulcers which are non-tender, indurated, firm, and have abundant beefy-red granulation tissue at the base (image A).
Transmission: only mildly contagious.
Ulcers contain abundant granulation tissue with numerous large histiocytes containing the dark particulate inclusions (Donovan bodies) that are best seen on silver stain (image B).
Diagnosis must be established by microscopy because the bacilli are not readily cultured.
Treatment: antibiotics are usually curative, although relapse may occur if the antibiotics are discontinued too early.