So known as paraffinoma, sclerosing lipogranuloma, and Tancho's nodules.
Clinical: usually seen in men <40 years; localized mass or indurated plaque that may be tender to palpation.
Penile lesions are usually due to injection of paraffin, silicone, oil, or wax (purportedly for sexual gratification or penile enlargement).
Scrotal lesions are usually due to injection of foreign material, trauma, cold weather, and topical application of ointment.
The lesion consists of lipid vacuoles embedded in a sclerotic stroma.
Often accompanied by a granulomatous reaction with foreign-body giant cells.
Diagnosis may be confirmed by doing lipid stains.
Differential diagnosis: malakoplakia or signet ring carcinoma.