Patients present with normal external genitalia, well-developed secondary sex characteristics, and azoospermia.
Elevated FSH, normal/elevated LH, and normal/low testosterone.
Seminiferous tubules contain only Sertoli cells with rare scattered spermatogonia.
Low-power impression is a "wind-swept" appearance to the tubules
Five variants have been described, based upon the nature of the Sertoli cells.