Chronic urinary tract infection characterized by calcium salt deposits in bladder mucosa.
Results from inorganic salt deposition in mucosa due to urine alkalinization by urea-splitting bacteria (most commonly Corynebacterium urealyticum).
More common in females.
Cystoscopy may show gritty encrusted mucosa (image A).
Fibrinous exudates admixed with calcified necrotic debris and mixed inflammatory cellular infiltrates (image B).
Treated with antibiotics and acidification of urine.