Home Education AUAUniversity Education Products & Resources Pathology for Urologists Urinary Bladder Mesenchymal and Other Tumors Vascular Tumors

Vascular Tumors

Image A

Image B


  • Benign vasoformative tumor composed of endothelial cells.
  • Cystoscopy shows bluish nodular bladder lesion; can be multifocal.
  • Mostly are cavernous type and tumor cells lack cytologic atypia (image A).
  • Some lesions may represent vascular malformation.
  • Immunohistochemistry: like normal endothelial cells, expresses CD31 and CD34 (rarely necessary for diagnosis).


  • Malignant vasoformative tumor arising from endothelial cells.
  • Very rare in the bladder.
  • Histologically, have more atypical spindle and epithelioid cell features (image B).
  • Immunohistochemistry: expresses CD31 and CD34 (for confirmation).