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Pathology for Urologists

Encrusted Cystitis


Image A
(click on the image above)

Image B
(click on the image above)

  • Chronic urinary tract infection characterized by calcium salt deposits in bladder mucosa.
  • Results from inorganic salt deposition in mucosa due to urine alkalinization by urea-splitting bacteria (most commonly Corynebacterium urealyticum).
  • More common in females.
  • Cystoscopy may show gritty encrusted mucosa (image A).
  • Histology:
    • Fibrinous exudates admixed with calcified necrotic debris and mixed inflammatory cellular infiltrates (image B).
  • Treated with antibiotics and acidification of urine.

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