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Pathology for Urologists

Eosinophilic Cystitis

Image A
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Image B
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  • Characterized by inflammatory infiltrates rich in eosinophils.
  • Occurs in patients of wide age range and is more common in females.
  • Three clinical settings:
    • Localized and non-specific reaction to bladder injury, such as transurethral resection procedure or invasive carcinoma.
    • Less often, in setting of allergy in which patients may also have asthma, allergic gastroenteritis or peripheral blood eosinophilia.
    • Rarely in parasitic infestation.
  • Histology:
    • Inflammatory infiltrates composed predominantly of eosinophils in lamina propria &/or muscularis propria (image A) & (image B).

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