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Pathology for Urologists

Prostatic Urethra

Image A
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Image B
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  • Prostatic urethra (image A) & (image B) and proximal portion of prostatic ducts (image C) & (image D) are lined by urothelial cells.
    • Thus, prostate can also have primary urothelial carcinoma.
    • More often, urothelial carcinoma arises from prostatic urethra and extends into the prostate via prostatic ducts or directly from suburothelium.

Image C
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Image D
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  • Urothelial carcinoma from urethral surface may spread within prostatic ducts without invading the prostatic stromal (remains carcinoma in situ).
    • Urothelial carcinoma seen within the prostate is not always invasive!
    • Stage as "Tispd" in the 2010 AJCC staging system.

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