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Pathology for Urologists

Idiopathic Scrotal Calcinosis


  • Occurs in two settings:
    • Calcification of a preexisting epidermal inclusion cyst (EIC) or pilar cyst.
    • Calcification of dermal connective tissue in the absence of a cyst (idiopathic).
  • Clinical: usually young men with a long history of multiple firm or hard nodules measuring up to 3 cm in diameter; overlying skin is generally intact although it may ulcerate and extrude cheesy material (like an EIC).
  • Histologic features: dermis contains globules of bluish calcific material with or without granulomatous inflammation.
  • Treatment: surgery as needed.

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