Pathology for Urologists
- Observed in monorchidism, cryptorchidism, and after testicular injury.
- Hypertrophy occurs prior to or during puberty, but thereafter the hypertrophic testis returns to normal or remains only slightly enlarged.
- Results from alteration in the hypophyseal hormonal feedback, which increases secretion of FSH and enlargement of the remaining testis.
Idiopathic Benign Macroorchidism
- Most likely a result of altered hormonal receptivity in the testicular parenchyma.
- Generally seen in pubertal and prepubertal patients.
- Increased mass is often due to increased length of the seminiferous tubules, but other minor changes may occur (increased tubular diameter, Leydig cell hyperplasia, etc.).