<p><strong> </strong><strong>When combining ADT with radiation therapy, clinicians may use combined androgen suppression (LHRH agonist with an antiandrogen), an LHRH agonist alone, or an LHRH antagonist alone. <em>(Expert Opinion)</em></strong></p>
Discussion
Discussion
<p>Various compositions of ADT have been used in combination with radiation in randomized trials to date. For example, a number of studies used combined androgen suppression for the entire course of treatment,<sup>275, 276, 278, 292, 295</sup> while other series used an LHRH agonist for the duration of treatment with an initial a short course of antiandrogen at the early phase of treatment,<sup>294, 296</sup> and some trials used LHRH agonists alone.<sup>286, 289</sup> The Panel believes that clinicians may use any one of these options in combination with radiation.</p>