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Clinically Localized Prostate Cancer: AUA/ASTRO Guideline (2026)
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Licenses for promotional or commercial use can be requested by contacting Keith Price at kprice@AUAnet.org.
Access FAQs on AUA clinical guideline usage and licensing.
By reading this guideline, you agree to AUA's Guidelines Terms and Conditions of Use.
Using AUA Guidelines
Access to AUA guidelines is provided free for individual clinical use only, in accordance with the AUA Guidelines Terms and Conditions of Use. Anyone accessing AUA guidelines for any other purpose must obtain a license/permission in advance. Licenses for academic, research and educational purposes (e.g., in course packs or employer-sponsored research) can be requested through the AUA by contacting permissions@AUAnet.org.
Licenses for promotional or commercial use can be requested by contacting Keith Price at kprice@AUAnet.org.
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Guideline Resources
Clinically Localized Prostate Cancer Guideline PDF
Amendment Summary for this Guideline
The Journal of Urology® Article
Purpose
Prostate cancer remains the most common non-cutaneous cancer among US men. As the vast majority of newly-diagnosed prostate cancer patients have clinically localized disease, providing evidence-based guideline statements to support clinical decision-making represents an important component of facilitating the delivery of standardized, high-quality care.
Key Takeaways
The recommendations discussed herein for the management of clinically localized prostate cancer provide a framework stratified by risk to facilitate care decisions and guide clinicians in the implementation of selected management options:
- Risk assessment
- Staging
- Risk-based management
- Principles of management
- Active surveillance
- Surgery
- Radiation
- Follow-up after treatment
The importance of shared decision-making between patient and clinician is emphasized in the statements and supporting text. Further, the guideline outlines specifics of care delivery for various therapeutic modalities while also identifying several areas of ongoing study that are likely to be of significant relevance in the future for the care of patients with clinically localized disease.
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AUA Clinical Practice Guidelines are developed by multidisciplinary panels of experts based on rigorous systematic review of current urologic research.
| Free Resources | |
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Urology A-Z Clinically Localized Prostate Cancer |
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| Member Benefit | |
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Clinically Localized Prostate Cancer Guideline PDF |
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Amendment Summary for this Guideline |
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The Journal of Urology® Article |