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Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline
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Licenses for promotional or commercial use can be requested by contacting Keith Price at kprice@AUAnet.org.
Access FAQs on AUA clinical guideline usage and licensing.
By reading this guideline, you agree to AUA's Guidelines Terms and Conditions of Use.
Using AUA Guidelines
Access to AUA guidelines is provided free for individual clinical use only, in accordance with the AUA Guidelines Terms and Conditions of Use. Anyone accessing AUA guidelines for any other purpose must obtain a license/permission in advance. Licenses for academic, research and educational purposes (e.g., in course packs or employer-sponsored research) can be requested through the AUA by contacting permissions@AUAnet.org.
Licenses for promotional or commercial use can be requested by contacting Keith Price at kprice@AUAnet.org.
Access FAQs on AUA clinical guideline usage and licensing.
By reading this guideline, you agree to AUA's Guidelines Terms and Conditions of Use.
Using AUA Guidelines
Access to AUA guidelines is provided free for health care providers for their individual clinical use only. Patients and the general public are provided a summary of the guidelines. Patients who wish to discuss the full guidelines should consult with their healthcare provider.
Guideline Resources
Male Infertility Guideline PDF
Male Infertility Amendment Summary
Male Infertility Algorithm
(Published 2020; Amended 2024)
Purpose
Infertility is due in whole or in part to the male in approximately one-half of all infertile couples. Some male factor conditions are treatable with medical or surgical therapy. Some conditions are life threatening, while others have health and genetic implications for the patient and potential offspring. A male evaluation is necessary to adequately design the management of the patient and the couple. The purpose of the Guideline is to outline the appropriate evaluation and management of the male partner in an infertile couple.
Key Takeaways
The true prevalence of male infertility is not clearly defined due to multiple factors, including variations in definitions of infertility, differences in sources of data, and the population being studied. Recommendations included in this Guideline discuss the following:
- Initial assessment
- Lifestyle factors and relationships between infertility and general health
- Diagnosis and evaluation
- Imaging
- Treatment
- Varicocele repair/varicocelectomy
- Sperm retrieval
- Obstructive azoospermia, including post-vasectomy infertility
- Medical and nutraceutical interventions
- Gonadotoxic therapies and fertility preservation
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AUA Clinical Practice Guidelines are developed by multidisciplinary panels of experts based on rigorous systematic review of current urologic research.